Cardiologists reveal cholesterol drug which has ability to . It means that for anyone who we know has coronary disease, we can switch it off.'Other experts urged caution, stressing that drug company Amgen, which makes Repatha - has not yet proven it can actually stop heart attacks or save lives. Any treatment that reverses the build- up of plaques in the arterties, known as atheromas, significantly reduces the risk of a heart attack. The company hopes a far larger trial, of nearly 3. March. An estimated 3. The third in a five-part series of articles that explain the new heart disease and stroke prevention guidelines. There have been a lot of questions about the new.
UK are already eligible for Repatha and a similar drug called Praluent, after NHS watchdog NICE approved the drugs in May. That approval was made on the basis of trials which showed they reduced cholesterol by about 6. But the new evidence is the first to show they actually reverse the cause of heart disease, and could mean many more become eligible in the future. The drugs - the first cholesterol treatments since statins were developed 3. They have been approved in the UK for two main groups – those with a genetic condition which means they have dangerously high cholesterol, and people with heart disease who cannot cope with the side effects of statins. But the new findings suggest the drugs could benefit hundreds of thousands more people - with up to 1. The researchers, led by the Cleveland Clinic in Ohio, found patients were still seeing their plaques shrink even when their cholesterol levels had reached very low levels - about a tenth of the level at which British patients are eligible for the drug. Study leader Dr Steven Nissen, whose work was published last night in the JAMA medical journal, said: 'That is unprecedented.'We didn't know what would happen to disease progression at LDL cholesterol levels when we went so low.'I thought there would be diminishing returns at low levels, but we did not see that.'So even when you get to very low cholesterol levels you have a really high chance of your plaques melting away.'That is really quite extraordinary.'Repatha, which is also known as evolocumab, and Praluent, known as alirocumab, has so far been given to only handfuls of NHS patients, mostly because the of the cost. Both drugs cost about . Of these, they calculated 1. The main drugs not being prescribed were statins, anticoagulants, and anti- hypertensives. Cancer does kill a lot of women. Among Americans aged 30 to 74, most have hearts that have aged beyond their chronological years; The average predicted heart age for adult men and women was 7.8 and 5. Probiotic Foods to Add to Your Diet 1. One of the best probiotic foods is live-cultured yogurt, especially handmade. Look for brands made from goat GPs failing to prescribe the drugs may 'overestimate side effects and underestimate the benefit for elderly patients,' the researchers wrote in the journal PLOS Medicine. They used records of more than 5. GP surgeries and found 2. Of these, 1. 7,6. The British Heart Foundation's Dr Mike Knapton said the study was a 'stark warning'. Endurance athletes who exercise for three hours or more have an increased chance of dying from a cardiac arrest. About 1 in 50,000: if you run marathons or.
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